"Some naive people like the idea of negotiating with America, however, negotiations will not solve the problems," Khamenei said in a speech to officials and members of Iran's aerospace force, IRIB reported.

"If some people want American rule to be established again in Iran, the nation will rise up to face them," he said.

"American policy in the Middle East has been destroyed and Americans now need to play a new card. That card is dragging Iran into negotiations."

Khamenei made his comments just days after Joe Biden said the United States was prepared to meet bilaterally with the Iranian leadership. "That offer stands but it must be real and tangible," Biden said in a speech in Munich.